247 Metabolic signaling in sebaceous gland homeostasis
نویسندگان
چکیده
منابع مشابه
Diffuse sebaceous-gland hyperplasia.
Diffuse sebaceous-gland hyperplasia is a rarevariant of sebaceous-gland hyperplasia that isdistinct from the well-known circumscribed type.The term presenile sebaceous hyperplasia has beenutilized to describe this entity that is distinguishedby specific features, which include confluence oflesions that results in the formation of large plaqueson the face, the sparing of periorificial regions, a...
متن کاملSebaceous gland lipids.
The principal activity of mature sebaceous glands is producing and secreting sebum, which is a complex mixture of lipids. Sebum composition is different among species and this difference is probably due to the function that sebum has to absolve. In human sebum there are unique lipids, such as squalene and wax esters not found anywhere else in the body nor among the epidermal surface lipids. Mor...
متن کاملHistogenesis of Sebaceous Gland Carcinomas
Tumors produced by 2-acetylaminofluorene occur with differing frequencies in various organs. The squamous-cell carcinomas of the auditory canal region, reported in the original experiment of Wilson, De Eds, and Cox (23), appear to be of particular interest. There has been considerable discussion in the literature as to their site of origin and mode of development. In our experiment this type of...
متن کاملLrig1 Expression in Human Sebaceous Gland Tumors
BACKGROUND Sebaceous glands contribute significantly to the barrier functions of the skin. However, little is known about their homeostasis and tumorigenesis. Recently, increased expression of stem cell marker Lrig1 has been reported in sebaceous carcinoma-like tumors of K14ΔNLef1 transgenic mice. In this study, we analyzed the Lrig1 expression in human sebaceous tumors. METHODS Twenty-eight ...
متن کاملSebaceous adenoma in the submandibular gland.
An otherwise healthy 38-year-old woman sought treatment for a right-sided progressively enlarging submandibular mass of 3 years’ duration. No significant personal or family history of malignancy was noted. The mass was initially measured as 2 × 1 cm. Three years later, on palpation, the mass was over the right submandibular area and was measured as 4 × 3 cm. It was soft and movable without tend...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2017
ISSN: 0022-202X
DOI: 10.1016/j.jid.2017.07.245